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Josi Holz has over 20 years of experience in the medical field. Josi began their career in 2001 as Medical Director at Allos Therapeutics, Inc. In 2004, they moved to GPC Biotech as Director of Clinical Trials and Safety. In 2005, they joined U3 Pharma as Vice President of Drug Development. From 2007 to 2013, they were Chief Medical Officer at Ablynx NV. From 2013 to 2015, they were Vice President of LEO Project Management at LEO Pharma A/S. In 2018, they took on the role of Clinical Advisor at Calypso Biotech. In 2020, they became Chief Medical Officer at Synklino and STORM Therapeutics Limited. Currently, they are Chief Medical Officer at Prokarium. Additionally, since 2015 they have been an Independent Business Owner at Josefin-Beate Holz "Bioneer-Consulting".

Josi Holz obtained an MD from The Philipp University of Marburg between 1986 and 1991, with a field of study in Medicine, Pharmacokinetics, and TOF Mass Spectorometry.