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Cari Manypenny has a diverse work experience in the healthcare industry. They began their career in 2009 as a Speech-Language Pathologist at Marianjoy Rehabilitation Hospital. In 2015, they transitioned to the role of Clinical Development Coordinator at the same hospital, where they stayed until 2021. During their time at Marianjoy Rehabilitation Hospital, Cari also worked as a Clinical Specialist at Phagenesis Ltd from 2017 to 2021. In February 2021, they became the Manager of Clinical Development at Phagenesis Ltd.

Cari Manypenny's education history begins in 2003 when they enrolled at Illinois State University to pursue a Bachelor's degree in Speech Pathology and Audiology. Cari completed their undergraduate studies in 2007. After obtaining their Bachelor's degree, Cari continued their education at the same institution, Illinois State University, from 2007 to 2009 to earn a Master's degree in Communication Sciences and Disorders.