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Henrike Ruehl has a diverse work experience spanning several industries. Their most recent position is with Patient21, where they serve as the Chief of Staff. Prior to that, they worked as a Founder's Associate at the same company. Before joining Patient21, Henrike was employed at etventure as a Project Manager and Junior Project Manager. Henrike also worked as a Student Consultant at Franklin Templeton, a Digital Marketing Intern at BMW Group, and a Strategy Intern at TLGG. Additionally, they gained experience as a Sales Operations Intern at GetYourGuide, a Room Service Intern at Four Seasons Hotels and Resorts, and held various intern positions at Brenners Park-Hotel & Spa, ESCADA, and Henkel.

Henrike Ruehl's education history starts with their completion of the International Baccalaureate at Haileybury UK from 2009 to 2011. Henrike then pursued a Bachelor of Arts degree in International Hospitality Management at IU International University of Applied Sciences from 2012 to 2016. During their studies, they also completed a Bachelor's Degree in International Hospitality Management Top-Up at the University of Brighton from 2014 to 2015.

Henrike furthered their education by obtaining a Master of Science degree in Management from Imperial College Business School from 2017 to 2018. In addition to their academic qualifications, they have pursued additional certifications, including AI Foundations from IBM (obtained in February 2021), Professional Scrum Master from Scrum.org (obtained in January 2021), Rhetoric: The Art of Persuasive Writing and Public Speaking through HarvardX - An Online Learning Initiative by Harvard University (obtained in April 2020), and WSET Level 2 Awards in Wines and Spirits from the Wine & Spirit Education Trust (obtained in June 2015).