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Sara Chalk's work experience includes roles as a Manager Animal Sciences at Kymab Ltd starting in 2011, Senior Research Officer at IRB Barcelona from 2007 to 2010, Staff Research Associate at the University of California, Davis from 2003 to 2007, and Scientific Officer at Cancer Research UK from 1998 to 2003.

Sara Chalk's education history includes attending the University of the West of England, where they obtained a Bachelor's degree with honors in Biology, General. Additionally, they attended Langleybury School, although no specific degree or field of study is noted for this institution.