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Mary Scamacca has worked in various senior leadership roles throughout their career. Mary began their career at Meridian Capital Markets in 1989 as a Director. Mary then joined First Niagara Bank in 1999 as a Senior Vice President in the Enterprise Project Management Office (EPMO), where they stayed until 2016. Mary then joined KeyBank as a Senior Vice President in the EPMO from 2016 to 2019. Mary continued their career at Life Storage as the Vice President of the Program Management Office/Acquisitions from 2020 to 2023. Currently, Mary holds the position of Senior Director of the Strategic Enterprise Project Management Office at Kaleida Health, which they started in 2023.

Mary Scamacca has a Bachelor of Business Administration (BBA) degree in Business Administration and Management, General from Daemen University.