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Jeff Hoffmeister has a diverse work experience in the medical field. Jeff started their career as a Radiology Resident at Barnes-Jewish Hospital in 1989. Jeff then worked as a Director of Radiology and Primary Care Physician at the Los Angeles Air Force Base Clinic from 1990 to 1993. Following this, they joined the USAF Armstrong Laboratory as a Research Manager, Electrical Engineer, Flight Surgeon, and achieved the rank of USAF Major. From 1997 to 2000, Jeff co-founded Qualia Computing, Inc. where they served as a Co-Founder, Medical Director, Board Member, and Secretary/Treasurer. After that, they worked as a Medical Director at CADx Medical Systems from 2000 to 2003. Currently, they hold the position of VP, Medical Director at iCAD, Inc. since 2004.

Jeff Hoffmeister completed their education at various institutions. Jeff attended North Hills High School, although the start and end years are not provided. Jeff then went on to obtain a B.S. in Electrical Engineering from Valparaiso University, graduating in 1985. Jeff continued their education at Washington University School of Medicine in St. Louis, where they earned an M.D. degree in Radiology between 1985 and 1989. Lastly, they pursued a Master's degree in Electrical Engineering from California State University, Long Beach, completing their studies from 1991 to 1997.