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Rhona Macdonald has a diverse work experience in the healthcare and pharmaceutical industries. Rhona began their career in 1999 as a Staff Nurse at Oxford University Hospitals NHS Foundation Trust, where they rotated between cardiology and coronary care roles. Rhona then worked as a Senior Staff Nurse in coronary care at the Royal Melbourne Hospital before joining Guy's and St. Thomas' NHS Foundation Trust as a Senior Staff Nurse in day case cardiology.

Rhona later moved to New Zealand and worked at Auckland DHB as an Interventional Cardiology Trial Coordinator. Rhona then joined the Mercy Angiography Unit, where they served as a Senior Staff Nurse in interventional cardiology and later became the Team Leader for interventional cardiology trials.

In 2013, Rhona joined Quintiles as a Regulatory & Start-up Specialist, and in 2016, they transitioned to Douglas Pharmaceuticals as a Senior Clinical Research Associate. Over the years, they have held various roles at Douglas Pharmaceuticals, including Clinical Trial Manager, Clinical Operations Manager, and currently, Head of Clinical Research.

In April 2020, Rhona also took on a role as a General and Obstetric Nurse at the Ministry of Health New Zealand as part of the country's COVID-19 response.

Rhona Macdonald completed their education history as follows:

From 1989 to 1995, Rhona Macdonald attended Grantown Grammar. Rhona did not pursue a specific degree or field of study during this time.

From 1996 to 1999, Rhona Macdonald enrolled at the Argyll and Clyde College of Nursing and Midwifery. However, the provided information does not specify whether they obtained a degree or studied a specific field.

Lastly, from 2011 to 2014, Rhona Macdonald attended Victoria University of Wellington where they acquired a Postgraduate Diploma in Clinical Research.