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Delphine Issard has a strong background in biostatistics and has worked in the field for over 20 years. Delphine started their career as a Biostatistician at delta consultants in 2001 and remained in this role until 2006. Delphine then joined Serono as a Biostatistician for a few months before transitioning to a Biostatistician role at Merck Serono International, where they worked from 2006 to 2012. During their time at Merck Serono International, they also took on the role of Associate Director of Biostatistics at Cytel in 2018, where they currently work.

Delphine Issard attended Université Joseph Fourier (Grenoble I) from 1996 to 2001, although no specific degree or field of study was mentioned. In 2017, they obtained a certification in "Adaptive Designs for Clinical Trials" from Statistics.com.