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Sheila Murphy has a diverse work experience spanning over three decades. Sheila started their career in 1986 as a Senior Programmer/Analyst at Fidelity Investments, where they worked until 1990. After that, they worked at Melrose Public Schools as a Computer Aide from 2000 to 2002. Following this, they joined Doherty, Cella, Keane LLP as a Legal Assistant from 2003 to 2012. At MIT, they worked as a Legal Assistant in the Office of the General Counsel from 2012 to 2021. Currently, they hold the position of Executive Assistant to the Chief Financial Officer and General Counsel at Xilio Therapeutics, Inc. starting from April 2021.

Sheila Murphy holds a Bachelor of Science degree in Computer Information Systems from Bentley University. No specific start or end year for their education at Bentley University is provided.