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Manu Jain has worked in the field of Extended Reality since 2021, when they became the Chief Extended Reality Officer and Head of AR/XR for Vector Space Biosciences. Prior to this, they were a VR/AR Production at New Reality Co. from 2019-2021 and an Emerging Technology Consultant at the Tenement Museum in 2019. From 2015-2019, they were the Co-Founder and Producer/Director of VR and Traditional Films at Dose of Reality Productions. From 2011-2015, they were Manager of Programmatic Video Product Growth and Creative Manager of Entertainment at Tremor Video. From 2008-2011, they were Manager of Product Management & Marketing at JovianDATA, Inc., which was acquired by MarketShare Partners in August 2010. Finally, from 2007-2008, they were a Business Development at Universal Music Group.

Manu Jain attended Bellarmine College Preparatory for high school. Manu then went on to pursue a Bachelor's Degree in Business Strategy and Film from Northwestern University. Following their undergraduate studies, Manu Jain obtained a Master's Degree in the ITP Program (Interactive Technology Program) from New York University. In 2015, Manu Jain obtained a Filmmaking certification from the New York Film Academy.