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Samuel Hess began their career in 2013 as a Postdoktorand and PHD at ETH Zürich. In 2016, they took on a PHD - Project (JSPS) at the University of Hiroshima. In 2018, they became the CEO of UniSieve AG.

Samuel Hess obtained a BSc ETH Biotech in Biotechnologie from ETH Zürich between 2008 and 2011. Samuel then completed an MSc ETH Biotech in Biotechnologie from ETH Zürich between 2011 and 2013. During this time, they also completed a Research Project in Chemical and Biomolecular Engineering at the University of California, Berkeley in 2012.