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Brent Clough co-founded Trio Health in 2013. Prior to this, Brent founded IntrinsiQ Financial in 2004, which merged with IntrinsiQ Research in 2006. IntrinsiQ is the leader for oncology clinical software that tracks and manages complex chemotherapy workflows. IntrinsiQ developed the largest longitudinal patient database that has been widely adopted by the pharmaceutical companies. Upon the merger, Brent was elected President and CEO of the company. The company grew from a start-up to 90 employees prior to being acquired by Amerisource Bergen.

Before entering the healthcare industry, Brent spent eight years as a Vice President at Goldman Sachs (1996-2004) working in the investment research and equities division. Prior to Goldman, Brent worked at First Call Corporation (1988-1996) within the institutional sales and broker dealer division.