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Annamaria De Biase has a diverse work experience in the semiconductor and aerospace industries. Annamaria started their career in 1988 as a Microelectronic Technologist at ELETTRONICA S.p.A. Annamaria then worked at Texas Instruments from 1992 to 1998, where they held roles as a Process Engineer in both the Semiconductor Division and R&D Consumer Division. In 1998, Annamaria joined Micron Technology, where they worked as a Metal/Implant Section Manager and later as a Senior Process Integration Engineer. Since 2010, they have been working at Thales Alenia Space, initially as the Head of Microelectronic Technologies and currently as the Head of Hybrid Manufacturing. Throughout their career, Annamaria has gained expertise in various areas such as industrial engineering, microelectronic technologies, and process integration.

Annamaria De Biase has a background in physics and attended Sapienza Università di Roma, though no specific degree is mentioned for this period. Prior to that, from 1974 to 1979, they studied at Liceo Ginnasio "Giulio Cesare" in Roma, but no specific field of study or degree was provided.