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Debra MacDonald has extensive work experience in the retail industry. Debra began their career at Holt Renfrew in 1979, where they held roles as a Sales Associate and Department Manager. Debra then moved on to Brettons in 1986, where they worked as a Store Manager until 1993. After that, they joined Penningtons as a District Manager for a year. In 1995, Debra joined Staples Canada and held various positions including General Manager, District Manager, Regional VP for Central Canada, and most recently, they serve as the National VP of Operations.

Debra MacDonald attended Beaconsfield High School from 1972 to 1977. No degree or field of study was specified.