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Wilhelm Huck has worked at Radboud University Nijmegen since 2010, where they are currently a Professor of Physical Organic Chemistry. Wilhelm is also the Founder and Director of Sphere Fluidics Limited, which they have been since 2010, and Co-founder of Cytofind Diagnostics since 2014. Prior to their current roles, they were a Professor of Macromolecular Chemistry at the University of Cambridge from 2007.

Wilhelm Huck completed a postdoctoral degree at Harvard University from 1997 to 1999 in the field of Chemistry. Wilhelm then went on to obtain a PhD in Chemistry from the University of Twente between 1992 and 1997. Prior to that, they earned an MSc in Chemistry from Leiden University between 1988 and 1992.