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Dr. Orelien is the CEO and President of ScitoVation, LLC a company that helps clients assess the safety of chemical products using in vitro and in silico methods (non-animal approaches). ScitoVation is the recognized leader in the use of innovative science and next-generation technology for assessing chemical safety. Clients of ScitoVation include the American Chemistry Council, the American Beverage Association, and fortune 500 companies.

Prior to ScitoVation, Dr. Orelien served as CEO of SciMetrika, LLC a company he co-founded in 2001. SciMetrika was sold in September 2018 to Inoventures, a federal contractor based in northern Virginia. During Dr. Orelienā€™s tenure, SciMetrika achieved more than $100M in billings and performed on more than 150 federal contracts or task order awards. SciMetrika has received numerous awards for growth, including in 2010 the North Carolina Council for Entrepreneurial Developmentā€™s Companies to Watch, as well as Inc. magazineā€™s Top 500 Fastest Growing Companies in both 2010 and 2011. SciMetrika made the list of fastest-growing companies in the Triangle four times finishing #2 in 2012.

Dr. Orelien has been honored as one of Inc. magazineā€™s Top 10 Black Entrepreneurs (2010 and 2011), top 50 African-American in science and technology by Black Money, and in 2011 received the James E. Grizzle Distinguished Alumni Award from the University of North Carolina at Chapel Hillā€™s (UNC) Department of Biostatistics. He serves as an adjunct professor at the UNC School of Public Health and a board member of the UNC Public Health Foundation (the advisory board for the School of Public Health).