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Marie-José Hoefmans has a diverse work experience spanning over several roles and industries. Marie-José co-founded Schluss in 2015 and served as the Chief Essential Officer. Previously, they owned and worked as a freelance consultant in marketing and communications at Dock23 since 2008. Marie-José also worked as a Marketing-Communication Manager at Infologic from 2010 to 2011 and as a Senior Marketing Professional at Techxx in 2010. Additionally, Marie-José worked as a Product Manager/Marketing Communications Manager at Centa from 2004 to 2009. Before that, they were a Teacher of Text Processing at Hogeschool Tio from 2002 to 2004. Marie-José started their career as a Marketing Communications Officer at Nissan Motor Parts Centre (Europe) B.V. from 1989 to 1995 and began as a trainee at Nestlé Nederland B.V. in 1989.

Marie-José Hoefmans attended Mendel College Haarlem from 1978 to 1986, where they obtained a VWO - bèta degree. Following that, they enrolled at Inholland University of Applied Sciences from 1986 to 1989, pursuing a field of study in HEAO-CE.