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Sameer Jafri's work experience includes serving as the CEO of Avive Solutions Inc. starting in March 2022, and previously as the President & COO from June 2017 to February 2022. Sameer is also the Founder and President of the Saving Hearts Foundation since October 2014, where they focus on preventing Sudden Cardiac Arrest through awareness, education, and action. In addition, Sameer co-founded Twazer, a mobile application aimed at creating a safe and efficient marketplace for college students to buy and sell items from each other, from May 2015 to April 2017. Sameer worked as a Paid Intern/Clinical Research & Laboratory Assistant at Immunicom Inc. in June 2014, and as the Desk Manager/Coach at Coast Baseball & Sports Fitness from July 2012 to January 2013. Furthermore, Sameer served as an Assistant Coach for the California Lookouts from February 2012 to May 2012.

Sameer Jafri completed their Bachelor's degree in International Relations and Affairs from UCLA, where they attended from 2013 to 2017. Prior to that, they attended Canyon Crest Academy from 2009 to 2013, where they pursued General Studies.