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Shane Ryan began their work experience in 2006 as a Radiology Manager at Saint Francis Health System. In 2011, they transitioned to the position of Director, Invasive Cardiology at the same company. In 2010, they also took on the role of Adjunct Instructor at St. Gregory's University. Their work at these organizations lasted until at least 2016.

Shane Ryan earned a Bachelor of Science degree in Radiologic Technology/Science - Radiographer from the University of Oklahoma Health Sciences Center in 1999-2001. Later, from 2004-2007, they obtained a Master of Public Health (MPH) degree in Health/Health Care Administration/Management from the University of Oklahoma.