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Crista sustained a C5 spinal cord injury in 1985 when she was 20 years old. She was awarded a scholarship from the Swim with Mike Physically challenged athletes fund at USC where she completed her BA and MS in 1991. She received her PhD in 2001 from Rutgers, The State University of New Jersey. Her postdoctoral fellowship, as well as her position as a research associate, focused on therapeutic strategies for treatment, regeneration, and recovery in spinal cord injury at the Keck Center for Collaborative Neuroscience.