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Brandi Hudson started their career in 2011 as an Adjunct Instructor at Trident Technical College. Brandi then worked as a Chemist I at o2si from 2011 to 2012. In 2014, they served as an NSF/JSPS Fellow at Kyoto University. From 2015 to 2015, they worked as a CCMSI Intern at Lawrence Livermore National Laboratory. In 2016, they became a Postdoctoral Scholar at UCSF. From 2018 to 2020, they worked as a Scientist I - Computational Chemistry at Relay Therapeutics, where they contributed to research programs and established the use of VCD measurements for small molecule configuration determination. From 2020 to 2021, they served as a Scientist II - Computational Chemistry and was also the founder and co-chair of the Diversity, Equity, Belonging & Inclusion Council at Relay Therapeutics. Finally, in 2023, they joined Remix Therapeutics as the Principal Scientist.

Brandi Hudson obtained their Bachelor of Science degree in Chemistry from the College of Charleston, where they attended from 2007 to 2011. Following their undergraduate studies, they pursued and completed their Doctor of Philosophy (PhD) degree in Chemistry at the University of California, Davis, spanning from 2012 to 2016.