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Swamy Yeleswaram has extensive work experience in the pharmaceutical industry. Swamy is currently serving as the Chief Development Officer (CDO) at Rapport Therapeutics since January 2023. Prior to this, they worked as an Entrepreneur in Residence at Third Rock Ventures from August 2022 to March 2023. Swamy also held various leadership roles at Incyte, including Group Vice President from February 2016 to August 2022 and Vice President from January 2002 to February 2016. Swamy started their career at DuPont Pharmaceuticals as an Associate Director from December 1998 to January 2002, and previously worked at Bristol-Myers Squibb as a Sr. Research Investigator from September 1992 to December 1998.

Swamy Yeleswaram obtained their Ph.D. in Pharmacokinetics from The University of British Columbia, where they studied from 1988 to 1992. Prior to that, they earned a Master's Degree in Pharmaceutical Sciences from Banaras Hindu University, completing their studies there from 1985 to 1987. Although information is not provided regarding the specified dates, Swamy Yeleswaram also attended Madras Medical College.