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Arghyotri Sinha has a diverse work experience spanning multiple companies and roles. In 2011, Sinha began their career as a Summer Intern at Jawaharlal Nehru University. They then joined Curadev in 2012 as a Project Fellow, where they worked until 2014 as a Research Biologist. Sinha was later promoted to the role of Senior Research Biologist at Curadev from 2016 to 2019. In 2019, they moved on to Syngene International Limited as an Associate Scientist, holding the position until 2022. Currently, Sinha is employed as a Senior Research Associate at Quanta Therapeutics since 2023.

Arghyotri Sinha pursued a Bachelor's degree in Microbiology from the University of Calcutta from 2007 to 2010. Following this, they went on to obtain a Master's degree in Biochemistry from the same university, which was completed between 2010 and 2012.