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Mary (Mimi) DeSouza has extensive work experience in the pharmaceutical industry. Mary (Mimi) is currently working as the Vice President, Product Team Lead at Prothena Corporation plc. Previously, they served as the Vice President Therapeutic Development Team Lead at Passage Bio and as the Executive Director at Bristol Myers Squibb. Mary also held roles at Merck, where they served as the Clinical Director, Project Lead Clinical Development and as the Associate Scientific Director and Associate Director in various areas. Additionally, they have experience in non-profit consulting as the Founder and CEO of DeSouza Consulting, where they provided pro-bono consulting services to non-profit organizations. Mary also served as a Council Member at Norrsitown Municipality. Prior to their consulting work, they held positions at GlaxoSmithKline, including Manager Clinical Drug Discovery and Investigator, where they played a key role in clinical research and drug discovery efforts.

Mary (Mimi) DeSouza pursued their education in a chronological manner. Mary (Mimi) started their academic journey at Tufts University from 1990 to 1995, where they earned their PhD in Molecular Biology, with a specialization in Women's Health. Following this, they attended Columbia University from 2003 to 2005 and obtained an MBA, although their specific field of study during this program is not provided.