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Arianne Domingo has a diverse background in business systems analysis, engineering, industrial engineering, product supply chain, and laboratory operations. Arianne began their career in 2012 as a Laboratory Operations Intern at Watson Pharmaceuticals, where they collaborated with the Laboratory Operations Director, Instrumentation, and Chemists to collect time standards and conduct process improvement for the testing of pharmaceutical products. In 2013, they became a Product Supply Chain Intern at The Coca-Cola Company. In 2014, they held two roles simultaneously, Business Systems Analyst III at Prolacta Bioscience and Industrial Engineering Intern at Eaton.

Arianne Domingo attended Palomar College from 2008 to 2011, studying Engineering. Arianne then went on to earn their Bachelor's Degree in Industrial Engineering from California State Polytechnic University-Pomona between 2011 and 2014.