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Sherman Tim Waddell

Founder, VP & Head of Chemistry at Prokaryotics

Tim brings 26 years of experience in leading chemistry lead identification/optimization programs in the areas of infectious and cardiometabolic disease, retiring from Merck as a Senior Investigator/Principal Scientist in 2016, To date, five compounds from his programs have entered the clinic. He is principal or co-author on 36 peer-reviewed papers and book chapters, and is an inventor on over 100 published and granted Merck patents. Prior to joining Merck, Tim received his PhD in 1988 from Yale University, where he studied physical organic and synthetic chemistry under Prof. K. B. Wiberg, and was an NIH post-doctoral fellow in the laboratories of Prof. E. T. Kaiser at The Rockefeller University and Prof. Ronald Breslow at Columbia University, where he pursued research in bioorganic and peptide chemistry. Tim is known for his scientific outreach, and speaks frequently to public audiences at the high school and college level about the mission, methods and challenges of the pharmaceutical industry.

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