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Shyamali Choudhury has a diverse work experience spanning multiple industries and roles. Starting in 2009, they worked as a Research Assistant at the City and County of San Francisco, Controller's Office of Economic Analysis. In 2011, they joined The Brookings Institution as a Senior Research Assistant and continued in that role until 2013. Then, they joined the Results for Development Institute as a Senior Program Associate, working there until 2014. In 2014, they started working at Pfizer as a Research Associate, focusing on Market Access, until 2015. Following this, they joined Flatiron Health in 2015 and held the position of Senior Director, Business Development until 2021. Currently, Shyamali Choudhury is working as the VP of Partnerships at Pomelo Care, starting in July 2021.

Shyamali Choudhury has pursued their education at Georgetown University and Washington University in St. Louis. At Georgetown University, they obtained a Master's in Public Policy (MPP), with a specialization in Economic and Social Policy. Additionally, they completed their Bachelor's degree (BA) at Washington University in St. Louis, majoring in Economics and French. The specific start and end years of their education at both institutions are not provided.