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Margaux Lejeune has a varied work experience. Margaux started their career in 2014 as a student, completing their Master's thesis at the University of Liège (ULg). In 2015, they joined the Institut Scientifique de Santé Publique (Sciensano) as a Collaboratrice scientifique in the Direction opérationnelle "Expertise, Prestations de service et relations clients". In this role, they were responsible for supervising and motivating teams of laboratory technicians, managing conflicts, writing and evaluating laboratory procedures (SOPs, etc.). In 2017, they became a Doctorante au Laboratoire d'Hématologie de l'Université de Liège at ULiège - Interface Entreprises. Most recently, in 2022, they began working as a Junior scientist at PDC*Line Pharma.

Margaux Lejeune obtained a Bachelier degree in Sciences Biomédicales from the University of Liège in 2009-2012. Margaux then went on to obtain a Master 2 degree in Sciences biomédicales à finalité approfondie, Option: Cancérologie et Immunologie from the same university in 2012-2014.