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Efrat Elis has held a variety of roles throughout their career. Efrat began as a Systems Engineer at IAI in 2005, then moved on to be a Teaching Assistant at Tel Aviv University in 2011. Efrat then became a Post Doc at the same university in 2013. In 2015, they took on the role of Quantitative Analyst, VP at an anonymous prop-trading company. In 2019, they became a Quantitative Analyst at Vanadium Algorithms, and currently holds the position of Senior Researcher at Pangea Biomed.

Efrat Elis holds a Doctor of Philosophy (PhD) in Virology from Tel Aviv University, which they obtained between 2008 and 2013. Prior to that, they earned a Bachelor of Science (BSc) in Life Sciences from Tel Aviv University between 2005 and 2008.