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Jon Melton has a diverse work experience spanning over 20 years. Jon started their career with Willis as an Account Handler in 2000 and worked there until 2003. Jon then joined Marsh as an Account Executive - Assistant Vice President from 2004 to 2005. In 2006, they moved to Aon Benfield where they worked as a Reinsurance Broker for over 11 years. In 2013, they co-founded Momentum Pharma Ltd and served as the COO. In 2015, they joined OWL Oncology Research as the UK & EU Managing Director. Most recently, in 2023, they co-founded airclinical.

Jon Melton attended the University of East Anglia from 1996 to 2000, where they earned a Bachelor's Degree in Business and Financial Services.