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Tonto Ngema has an extensive work history in the field of validation and quality control. They began their career at Alliance Pharmaceutical in 1995 as a QC Micro Analyst I/II. They then moved on to Imcor Pharmaceuticals in 2003, where they held the position of QC Micro Analyst II. In 2005, they joined Cell Genesys as a QC Micro Analyst II before transitioning to Genzyme GTO as a Validation Associate later that year. In 2011, Tonto joined Advance BioHealing Inc. as a Validation Engineer I, and the following year, they took on the role of Validation Engineer II at Shire. Their most recent position is at Organogenesis Inc., where they serve as a Validation Engineer III beginning in 2014.

Tonto Ngema has studied at San Diego City College, where they pursued a degree in Biology/Chemistry. However, specific information regarding the start and end years of their education at this institution is not available. Additionally, Tonto Ngema has also attended Universal College in Kenya, where they obtained a Certificate of ABE. During their time at Universal College, they focused on Accounting and Finance. The exact duration of their studies at this institution is not provided.