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Michael "Buz" Waitzkin has had a diverse range of work experience over the years. Michael "Buz" co-founded and served as a board member for Orbit Genomics, a genomic diagnostic and drug target discovery company. Prior to that, they worked at Duke University's Science & Society as the Deputy Director and Senior Lecturing Fellow. Michael "Buz" also worked as a Principal at Catawba Consulting and served as Of Counsel at James & Hoffman. Waitzkin has extensive experience in private law practice, both as a Partner and Litigation Counsel. Michael "Buz" also worked as a Trial Attorney at the Public Defender Service for the District of Columbia. Additionally, they have worked in the White House Counsel's Office as Special Counsel to the President. Overall, Waitzkin's work experience spans various roles in law, consulting, academia, and the biotech industry.

Michael "Buz" Waitzkin began their education at the University of Virginia, where they pursued a Bachelor of Arts degree in Government and Political Philosophy from 1967 to 1971. Following this, they attended Stanford Law School from 1971 to 1974, earning their Juris Doctor degree. After completing their legal studies, Waitzkin furthered their education at Yale Law School in 1974-1975, where they were a Commonwealth Fellow in Law, Science, and Medicine, obtaining a Master of Laws degree.