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Nicole Meyer began their work experience as an Editorial Assistant at Gonzo International in 1992. Nicole then went on to work as an Instructor of Microeconomics at Indiana University from 1996 to 1998. In 1998, they joined Charles River Associates as a Senior Associate, where they worked until 2007. From 2007 to 2009, they worked as a Manager at Analysis Group. In 2010, they joined Truven Health Analytics, an IBM Company, as a Researcher and held this role until 2018. Since 2018, Nicole has been working at Ontada, first as an Outcomes Researcher and currently as a Research Manager.

Nicole Meyer pursued their undergraduate education from 1988 to 1991 at Baruch College, where they earned a Bachelor of Business Administration (BBA) degree with a focus on Economics. Following this, they attended Indiana University Bloomington from 1995 to 1998, working towards a PhD (All But Dissertation) in Economics.