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Frank Compolo has extensive work experience in the medical field. Frank is currently serving as the Medical Director of Respiratory Therapy and an Attending Anesthesiologist at Oneida Health since 2021. Prior to that, they worked at American Anesthesiology as an Anesthesiologist/Intensivist from 2012 to 2021. Frank also has experience in primary care medicine and hospitalist roles at St Joseph's Hospital Health Center from 1998 to 2008.

Frank Compolo completed their Bachelor of Science degree in Biology, General at Siena College from 1987 to 1991. Frank then pursued their Doctor of Medicine degree at SUNY Upstate Medical University from 1991 to 1995. From 1995 to 1998, they completed their residency in Family Medicine at St Joseph's Hospital Health Center. Lastly, they attended the University of Rochester School of Medicine and Dentistry from 2008 to 2012, where they participated in the Anesthesiology Residency Program and Critical Care Fellowship.