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Wyatt Tole has worked in the medical field since 1999. Their first role was as a Medical Technologist at UT Southwestern Medical Center at Dallas. In 2001, they moved to Esoterix Infectious Disease Center as a Supervisor of Clinical Trials Services. In 2003, they became a Lead Medical Technologist at DRL Labs. From 2005 to 2007, they worked as a Medical Technologist at Denton Regional Medical Center (subsidiary hospital of HCA). Wyatt then moved to Texas Health Presbyterian Hospital Plano in 2007 as a Clinical Laboratory Scientist II. In 2009, they became a Supervisor Flow Cytometry CLS at NeoGenomics Laboratories. In 2014, they joined Ascend Genomics as a Manager Flow Cytometry and Director Laboratory Operations. Most recently, in 2018, they became the Director Clinical Flow Cytometry at Notable.

Wyatt Tole attained a Bachelor of Science (BS) in Medical Technology from Texas State University in 1996 and a Bachelor of Science (BS) in Biology from Stephen F. Austin State University in 1993. Wyatt also holds certifications as a Clinical Laboratory Scientist (CLS) from the State of California, a Medical Technologist from the American Society for Clinical Pathology (ASCP), and a Specialist in Cytometry (SCYM) from the American Society for Clinical Pathology (ASCP).