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John Lopos has a diverse work experience spanning over several companies in various roles. John began their career at Saatchi & Saatchi as a VP and Group Director. John then served as a Senior VP Group Director at Publicis. After that, they worked at sanofi-aventis as an Associate Director of Marketing and later as a Director of CNS Market Development. John then joined Datamonitor Healthcare as a US Director & Global Director-Consulting before moving to Triple Threat Communications as the EVP of Client Services and Commercial Strategy. John also worked at LiFT HSI as a Managing Principal. Currently, John is the CEO of National Sleep Foundation and a member of its Board of Directors.

John Lopos studied Psychology at Grinnell College. John also has a certification in Lean Six Sigma Black Belt, but no details about the institution or the year obtained are provided.