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Simone Guthrie (Sebastian) has a diverse work experience history. In 2014, they interned at Reynolds American Inc. as a Consumer Marketing intern and also had an internship at IBM in Sales and Distribution. Simone then joined Reynolds American Inc. and held various roles, including Lead Manager Consumer Marketing, Senior Manager Consumer Marketing, and Director of Brand Marketing. In 2020, they moved to Amazon as a Product Marketing Manager for B2B Payments. Simone later joined Levi Strauss & Co. in 2022 as a Senior Manager in Retail & Wholesale Marketing for Dockers. Currently, they are working at the Museum of Life and Science as the Vice President for Marketing and Communications.

Simone Guthrie (Sebastian) completed a J.D./M.B.A. degree in Marketing from Howard University in the years 2011 to 2015. Prior to that, they earned a Bachelor of Arts degree in Legal Studies from the University of Central Florida from 2009 to 2011. In 2020, they obtained a certification in "Strategies that Build Winning Brands" from Kellogg Executive Education.