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Sheela Thomas has a diverse work experience in the field of scientific research. Sheela began their career as a Postdoctoral Fellow at Stanford University in 2008 and held this position until September 2013. Sheela then worked as an LSRAII at Stanford University from October 2013 to January 2014. Sheela later joined Stanford University School of Medicine as a Laboratory Manager in February 2014 and held this role until February 2019. Sheela then moved to Chan Zuckerberg Biohub where they served as a Laboratory Manager from February 2019 to November 2022. Currently, they are working as a Scientist II at Maze Therapeutics starting from November 2022.

Sheela Thomas completed their education in a sequential manner. Sheela started their academic journey in 2000 by pursuing a Master of Science (MS) degree in Biology at Georgia State University. Sheela successfully completed this program in 2002. Subsequently, they continued their studies at the same institution and pursued a Ph.D. in Cell Biology and Physiology, which they attained in 2008. Following the completion of their doctorate, Sheela Thomas further enhanced their expertise by undertaking a postdoctoral fellowship at Stanford University from 2008 to 2013. The exact field of study during their fellowship is not specified.