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Sai Srinivas Panapakkam Giridharan is a Clinical Research Scientist at Machaon Diagnostics since October 2022, with previous experience as a Research Investigator at the University of Michigan from November 2013 to March 2022, where significant contributions included discovering the role of PIKfyve in neurological disorders and its regulation of endocytic recycling and cell migration. As a Postdoctoral Research Fellow, Sai identified methods to modulate phosphoinositide levels for Huntington's disease therapeutics. Earlier experience includes graduate studies at the University of Nebraska Medical Center, focusing on endosome biogenesis and actin microfilament regulation, and undergraduate studies at the Indian Institute of Technology, Madras, optimizing protocols for protein purification. Educational qualifications include a PhD in Biochemistry and Molecular Biology from the University of Nebraska Medical Center and a Bachelor's of Technology in Biotechnology from the Indian Institute of Technology, Madras.