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Lee Swem has a strong background in biosciences and research. From 2023, Lee has been employed as the Chief Development Officer at Kanvas Biosciences. Prior to this, Lee served as the Chief Scientific Officer at Federation Bio from 2019 to 2023. During this time, Lee also held the position of Vice President and Head of Research in 2019. Before joining Federation Bio, Lee worked at Achaogen as the Chief Scientific Officer, Senior Vice President from 2017 to 2018, and as the Vice President and Head of Research from 2015 to 2017. At Achaogen, Lee also worked as the Director of the Therapeutic Antibody Program from 2014 to 2015. Before Achaogen, Lee worked as a Consultant and Scientist at Genentech from 2010 to 2014. Lee's academic experience includes a post-doctorate position at Princeton University from 2005 to 2009 and a PhD graduate student role at Indiana University from 2001 to 2005.

Lee Swem earned a Bachelor of Science (BS) degree in Molecular Biology from Indiana University Bloomington in 1998. They later obtained a Doctor of Philosophy (PhD) degree in Microbiology, General from the same institution in 2005.