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K-T Varley has worked in a variety of roles since 2009. In 2009, they began a Postdoctoral Fellowship at the HudsonAlpha Institute for Biotechnology. In 2010, they Co-Founded and became a Scientific Advisor for Kailos Genetics. From 2013 to present, they have been an Investigator at the Huntsman Cancer Institute, and an Associate and Assistant Professor at the University of Utah School of Medicine.

K-T Varley obtained a Bachelor of Science in Computational Biology from Cornell University in 2003, and a Doctor of Philosophy in Computational Biology from Washington University School of Medicine in St. Louis in 2009.