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Henk-Jan Schoonbeek's work experience begins with their role as a Postdoctoral Researcher at Wageningen University, where they worked from 1996 to 2002. Henk-Jan then joined Université de Fribourg - Universität Freiburg as a post-doc from 2002 to 2009, focusing on the mechanisms of pathogenicity of Botrytis cinerea on various host plants and defense mechanisms of Arabidopsis against pathogens.

From 2009 to 2012, Henk-Jan Schoonbeek worked as a Postdoctoral Research Assistant at the John Innes Centre, contributing to multiple projects on Brassica pathology. Henk-Jan then continued their role as a Postdoctoral Research Assistant at the same institution from 2012 to 2019, where they conducted GWAS studies on 192 B. napus lines for disease assays, collected metabolomic samples, and managed data for the consortium's 7 member laboratories.

In 2015, Henk-Jan Schoonbeek served as a Consultant at CN Seeds Ltd until 2019, and their last known role is as a Postdoctoral Research Assistant at the John Innes Centre since July 2019.

Henk-Jan Schoonbeek's education history begins in 1985 when they attended Mencia de Mendoza Lyceum, where they obtained their VWO degree in Junior High/Intermediate/Middle School Education and Teaching in 1991. Henk-Jan then pursued further education at Leiden University from 1991 to 1996, earning a Master's degree in Chemistry and Molecular genetics. Finally, they enrolled at Wageningen University & Research from 1996 to 2000, where they obtained their Doctor of Philosophy (PhD) degree in Molecular Plant Pathology.