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Steven Finkbeiner and his lab study how brain cells learn and remember, and what causes them to malfunction or die in disease. The long-term goal is to understand how these normal functions go awry and cause neurological and psychiatric diseases. To this end, the lab has developed patient-derived models of several of them, including Huntington’s disease, Parkinson’s disease, amyotrophic lateral sclerosis (ALS), frontotemporal dementia, Alzheimer’s disease, autism and schizophrenia. The group has also developed state-of-the-art technologies to generate and analyze large troves of images and genetic data, including robotic microscopy and artificial intelligence.