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Since founding InterSystems in 1978, Mr. Ragon has led the company to worldwide prominence in the database, interoperability, and healthcare application markets.

Mr. Ragon is a Trustee of the Mass General Brigham health system as well as a Trustee of the Massachusetts General Hospital (MGH), where he also served as Honorary Co-Chair of the MGH Campaign. He is on the Harvard Medical School Board of Fellows. He is also a member of the MIT Corporation, the governing body of MIT, and is Co-Chair of the MIT Campaign.

In 2008, Mr. Ragon helped create the Ragon Institute, a joint research center of MGH, MIT, and Harvard. The vision of the Ragon Institute is to ā€œharness the immune system,ā€ and its immediate objective is the creation of a vaccine for HIV.