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Barclay Liliti started their work experience in 2010 at Edwards Lifesciences, where they served as the Director of Business Development. In this role, they contributed to the global leader in patient-focused medical innovations for structural heart disease and critical care. Barclay worked in areas including Clinical Affairs, Quality Engineering, Research & Development, Regulatory Affairs, Sales & Marketing, and corporate functions. Their work at Edwards Lifesciences lasted until 2017.

In 2018, Barclay joined Inspiren as the Senior Vice President of Medical Operations. At Inspiren, a nurse-led technology company, they introduced the world's first cognitive patient care assistant known as AUGi. AUGi serves as the gateway to all IoT connectivity and creates a true AI ecosystem through a revolutionary computer vision and hybrid sensing platform. Barclay's role at Inspiren involves intelligently analyzing interactions between providers and patients, room environmental factors, and medical equipment. Barclay is currently still employed at Inspiren.

Barclay Liliti attended Stuyvesant High School from 2000 to 2003, where they pursued a field of study in Biology, General. Later, from 2003 to 2009, Barclay obtained a Master's degree in International Business from Columbia University.