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Paul Sheiffele has been working in the biomedical research and drug discovery field since 1994. Paul began their career as a Research Assistant at Rockefeller University in 1994. Paul then moved on to become a Scientist at Wyeth Pharmaceuticals in 1996. In 1999, they became President of ingenious targeting laboratory, a leading world provider in customized gene targeting services. Most recently, in 2015, they became Co-Founder and Managing Partner of Hairpin Technologies Inc., an exclusive licensing agent of Cold Spring Harbor Laboratory for shRNA technology.

Paul Sheiffele completed a Bachelor of Arts in Neuroscience from Wesleyan University in 1994. Paul then went on to complete a Master of Public Health from Columbia University in 2002.