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Mitch Johnson has a diverse work experience, starting with their professional baseball career with the Boston Red Sox and Houston Astros from 1980 to 1989. Mitch then transitioned to sales and marketing roles at GlaxoSmithKline, where they served as a Sales Consultant, Regional and National Sales Trainer/Recruiter, District/Therapeutic Sales Manager, and Product Manager - Diabetes Franchise Marketing from 1989 to 2002. From 2002 to 2007, they were a Regional Vice President Sales at GlaxoSmithKline, leading sales teams in the southeastern regions and contributing to national teams. Following that, they worked at GlaxoSmithKline as an Executive Director, Influenza Franchise, US Vaccines Marketing for a year, responsible for marketing and commercializing the US Vaccines Flu portfolio. Mitch then joined LEO Pharma as the Vice President of US Sales, Dermatology from 2015 to 2017. Currently, they are working at Indivior, where they have held various positions including Head of Sales, Behavioral Health from 2017 to 2018, Vice President, US Sales from 2018 to 2023, Sr. Vice President, US Sales from 2023 to 2024, and currently holds the position of Sr. Vice President, US Commercial, Addiction Sciences from 2024.

Mitch Johnson earned a BSBA degree in Finance from Bryant University in 1987. Mitch then pursued an MBA degree at Duke University - The Fuqua School of Business from 1991 to 1993. Additionally, they obtained a Certificate in Transformational Leadership for Executives from The Wharton School, although the specific dates are not provided.