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Sarah Marzi investigates how genetic and environmental risk factors regulate the epigenome to influence neurodegenerative disease. Her group focuses on cell-type specific regulatory consequences of environmental risk factors for Alzheimer’s and Parkinson’s disease and how these interact with genetic risk variants. The Marzi lab combines experimental genomic and epigenomic techniques with innovative statistical and computational analyses to understand gene regulatory mechanisms contributing to the earliest stages of disease.

Dr Marzi completed her PhD in complex disease epigenetics with Jonathan Mill at King’s College London and worked as a postdoc with Vardhman Rakyan at Queen Mary University of London. She joined the UK Dementia Research Institute at Imperial College London at the end of 2019 as an Edmond and Lily Safra Research Fellow to establish her independent research group.