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Simone Mechler began their work experience in 1997 at Accenture, where they held the position of Senior Manager until 2010. In 2011, they joined Actelion, first as an eClinical Program & Change Manager and later as an Associate Director of eClinical Projects. From 2017 to 2022, Simone worked at Idorsia Pharmaceuticals Ltd, initially as an Associate Director of Clinical & Quality Systems, then as a Director and Team Lead, and currently holds the position of Senior Director and Team Lead of Clinical & Quality Systems. Additionally, they worked as a Diving Instructor at Sinai Divers from 2010 to 2011.

Simone Mechler completed their Abitur at Geschwister-Scholl-Gymnasium from 1978 to 1991. Simone then pursued a degree in Biology at The University of Freiburg from 1991 to 1997, with a focus on Microbiology, Biochemistry, Limnology, Data Processing & Statistics.