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John Seccombe has held various medical director positions in the field of cardiothoracic surgery. John started in 2017 as the Medical Director of Cardiothoracic Surgery at UnityPoint Health - Methodist and held this role until 2023. John then became the Medical Director of Cardiothoracic Surgery at Carle Health, specifically at Methodist Hospital in Peoria, IL starting from April 2023 onwards. Additionally, they have also served as the Heart Center Medical Director at HSHS St. Vincent Hospital Green Bay, although the specific dates for this role are not provided.

John Seccombe began their education at South Denver High School in 1974. John then attended Kent-Denver Country Day School from 1975 to 1977. John went on to earn a Bachelor of Arts (B.A.) degree in Biochemistry and Molecular Biology from the University of Colorado Boulder from 1977 to 1982. Following this, they attended the Mayo Clinic Alix School of Medicine from 1986 to 1990, where they obtained their Doctor of Medicine (M.D.) degree. John further pursued their medical education at the Mayo Clinic Graduate School of Biomedical Sciences, specializing in General Surgery from 1990 to 1996. Lastly, from 1996 to 1999, they completed a Cardiothoracic Surgery Residency at the Mayo Clinic Graduate School of Biomedical Sciences.